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Estradiol vaginal cream tube and three vaginal insert applicators in a blister tray

Vaginal Estradiol Combo: Cream + Tablets

42.5 grams, 0.01% Estradiol cream + 10 mcg Estradiol tablets · FDA-approved · Fragrance free

Dual-Action Vaginal Health Restoration

A comprehensive low-dose estradiol treatment designed to restore vaginal tissue, pH, and blood flow from multiple angles. The cream provides targeted topical relief, while the tablets deliver internal support directly to the vaginal canal, treating the full range of symptoms including dryness, itching, burning, painful sex, urinary urgency, and recurrent UTIs.

Why the Combo Works

  • Targeted and sustained relief: cream works where you need it; tablets deliver ongoing internal support
  • Relief in 2-4 weeks with continued improvement after
  • FDA-approved estradiol in both forms, clinically proven
  • Decades of evidence backing the approach
  • Flexible application: apply the cream to the vulva and urethra (the 'outside') on a schedule your MD outlines; use the applicator-based tablets as prescribed, inserting them into the vagina (the 'inside'), dissolving in place

Unlimited messaging with your MD, included.

How It's Prescribed

Your MD will confirm which combination is right for you and set your personalized dosing schedule. One monthly membership price covers your consultation, both medications, and shipping.

As low as $69 per month

Billed as $828 annually. Prepay 12 months and save 20%.

One monthly price covers the consult, medication, 6 automatic refills per year and unlimited texting with your MD. Nothing is billed per refill.

Ready to restore your vaginal health?

Prescription products require an online consultation and are dispensed only if a licensed MD determines they are appropriate.

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